GDNF

GDNF信息

英文名称:	Glial cell line-derived neurotrophic factors	上市药物数量	0
中文名称	神经胶质细胞系衍生神经营养因子类	临床药物数量	5
靶点别称	Glial Cell Line-Derived Neurotrophic Factors	最高研发阶段	申请上市

英文名称:	Glial cell line-derived neurotrophic factors
中文名称	神经胶质细胞系衍生神经营养因子类
靶点别称	Glial Cell Line-Derived Neurotrophic Factors
上市药物数量	0
临床药物数量	5
最高研发阶段	NDA/BLA

GDNF产品列表

属性
Protein (3)
产品库
在线 (3)
物种
Human (2)Mouse (1)
标签
Tag Free (2)His Tag (1)
标记
Unconjugated (3)

共 3 项数据

GDNF分子背景

Glial cell line-derived neurotrophic factor (GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta (TGF-beta) superfamily. It potently promotes the survival of of peripheral and central neurons. It signals through GFRα receptors, particularly GFRα1. Neuronal subpopulations that have been shown to be affected by GDNF include motoneurons, midbrain dopaminergic neurons, Purkinje cells and sympathetic neurons.

GDNF分子别名

GDNF,ATF

产品评论

2021-12-01
0人点赞
Human GDNF / ATF / hGDNF Protein, premium grade
Acro Biosystems' GDNF recombinant protein has proven to be a reliable and high-quality reagent for research focused on neuronal development and maturation. In my study involving cortical projection neuron cultures, GDNF consistently supported neuronal survival, neurite outgrowth, and the expression of maturation markers. Its batch-to-batch consistency and biological activity have made it an essential component in our differentiation protocols. I highly recommend this product to laboratories engaged in both fundamental neuroscience research and translational studies aiming to model neurodegenerative diseases or explore neuroprotective strategies.

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